Francesco Scognamiglio was born in 1975 in Pompei, the home and beating heart of Neapolitan culture. After graduating from the Naples College of Design in 1998, he opened his first fashion house. A fundamental moment in his career came in 1994, when he met Donatella Versace in Naples with whom he began a friendship and a working relationship that lasted until 1999.
His début with his first Couture collection was in July 2000. His first fashion show was held in Rome in the sumptuous halls of Palazzo Barberini, where he created an extraordinary blend of rock music and classical surroundings especially for the occasion. In fact, as the soundtrack for his show, he chose a live performance by the English band Skunk Anansie, and for his catwalk the top model Maria Carla Boscono.

It was in March 2001, however, that Francesco Scognamiglio made his début on the catwalks of the Milano Moda Donna fashion week. His collection was an enormous success, particularly among the international journalists. His woman - sedutive and ethereal - personified a conceptual glamour; not impudent and fancy but more exclusive, tending, collection after collection, towards experimentation with alternative fabrics and lines and shapes that are intentionally bold, but still in tune with the sensuality of the contemporary woman.

In October 2002, he had been named med Creative Director of Verri, for the launch of the first women collection of the brand proposed on the catwalk like preview during Man Fashion week in January. In Autumn 2008, he signed an agreement with the brand Allegri: the designer became the creative director of a special project named “01.01.09” and designed for three seasons the Woman and Man collection of the “fashion” department of the brand. In the meantime Francesco Scognamiglio signs a partnership with the private label from Bergamo Kabi Srl that starting from the Spring Summer 2008 season has been producing the prêt-a-porter collection of the designer.